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Related Experiment Video

Updated: Jul 11, 2026

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
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Parastomal hernia repair with acellular dermal matrix.

Joyce Aycock1, Alessandro Fichera, Janice C Colwell

  • 1Department of Surgery, University of Chicago Medical Center, Illinois, USA.

Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society
|September 19, 2007
PubMed
Summary
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Acellular dermal matrix for parastomal hernia repair shows recurrence rates similar to synthetic mesh. This method avoids stoma relocation and simplifies infection management, offering a viable alternative for complex hernia cases.

Area of Science:

  • Gastroenterology
  • Surgical Innovation
  • Biomaterials in Surgery

Background:

  • Parastomal hernias present significant treatment challenges due to high recurrence rates and wound contamination risks.
  • Current repair methods often involve synthetic meshes, which can complicate wound infections.

Purpose of the Study:

  • To evaluate the efficacy and safety of acellular dermal matrix (ADM) in parastomal hernia repair.
  • To assess recurrence rates and complication profiles associated with ADM use.

Main Methods:

  • A retrospective review of 11 patients undergoing parastomal hernia repair with ADM.
  • Data collected included ostomy type, prior repairs, comorbidities, surgical technique, complications, and recurrence.
  • Follow-up averaged 8.7 months.

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Main Results:

  • Three out of 11 patients experienced hernia recurrence.
  • Two patients developed wound infections, managed conservatively without implant removal.
  • A significant proportion of patients had underlying inflammatory bowel disease.

Conclusions:

  • Acellular dermal matrix demonstrates comparable recurrence rates to synthetic mesh for parastomal hernia repair.
  • ADM offers potential advantages by avoiding stoma relocation and simplifying management of wound infections.