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Updated: Jul 11, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

[Cutaneous protothecosis: case report].

Fabiana Pirani Carneiro¹, Mário Augusto P Moraes, Ana Maria G Rebêlo

¹Centro de Anatomia Patológica, Hospital Universitário de Brasília, Brasília, DF. fabianapirani@hotmail.com

Revista Da Sociedade Brasileira De Medicina Tropical

|September 19, 2007

Summary

A rare case of cutaneous protothecosis, a skin infection, was identified in an elderly man. Successful treatment was achieved using the antifungal medication itraconazole.

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Last Updated: Jul 11, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

Area of Science:

Dermatology
Mycology
Infectious Diseases

Background:

Prototheca species are algae that can cause opportunistic infections in humans, particularly those who are immunocompromised.
Cutaneous protothecosis is a rare manifestation of Prototheca infection, often presenting as chronic skin lesions.
The patient had a history of pemphigus foliaceus and phaeohyphomycosis, conditions that may affect immune status.

Observation:

A 78-year-old male patient presented with erythematous, infiltrated lesions on his right leg.
The patient was undergoing treatment for pemphigus foliaceus and phaeohyphomycosis.

Findings:

Histopathological examination confirmed the presence of Prototheca species in the skin lesions.
Fungal culture from the affected tissue also supported the diagnosis of cutaneous protothecosis.
The patient showed a positive clinical response to itraconazole therapy.

Implications:

This case highlights the importance of considering protothecosis in the differential diagnosis of chronic, non-healing skin lesions, especially in immunocompromised individuals.
Itraconazole appears to be an effective treatment option for cutaneous protothecosis.
Further research into the pathogenesis and optimal management of protothecosis is warranted.