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Updated: Jul 11, 2026
04:34
A Novel Non-invasive Method for the Detection of Elevated Intra-compartmental Pressures of the Leg
Published on: May 31, 2019
Systemic capillary leak syndrome associated with compartment syndrome
Masami Matsumura1, Yasushi Kakuchi, Ryoko Hamano
1Department of Nephrology and Rheumatology, Ishikawa Prefectural Central Hospital, Kanazawa. mmatsu@spacelan.ne.jp
Internal Medicine (Tokyo, Japan)
|September 20, 2007
Summary
Systemic capillary leak syndrome (SCLS) causes recurrent shock from leaky capillaries. Monitoring muscle compartment pressure during fluid resuscitation is crucial for SCLS patients.
Area of Science:
- Internal Medicine
- Hematology
- Critical Care Medicine
Background:
- Systemic capillary leak syndrome (SCLS) is a rare disorder characterized by recurrent episodes of plasma leakage from capillaries into interstitial tissues.
- This leads to sudden drops in blood volume (hypovolemic shock), hemoconcentration, hypoalbuminemia, and electrolyte imbalances.
Observation:
- A case study of a 26-year-old woman with SCLS experiencing recurrent hypovolemic shock.
- The patient presented with hemoconcentration, hypoalbuminemia, and monoclonal gammopathy, leading to an SCLS diagnosis.
- A subsequent SCLS episode three years later was complicated by pretibial compartment syndrome.
Findings:
- The case highlights the potential for severe complications in SCLS patients, including compartment syndrome.
- Prompt diagnosis and management of SCLS are essential to prevent life-threatening hypovolemic shock.
Implications:
- This case underscores the critical importance of monitoring muscle compartment pressures during fluid resuscitation in SCLS patients.
- Implementing compartment pressure monitoring can aid in timely intervention and potentially prevent complications like compartment syndrome.
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