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Updated: Jul 11, 2026
14:58
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
[Sneddon's syndrome: 15 cases with cerebral angiography]
1Service de Neurologie A et de Neuropsychologie, Hôpital des Spécialités, CHU Ibn Sina, Rabat, Morocco. elalaouifarism@yahoo.fr
Revue Neurologique
|September 20, 2007
Summary
Sneddon's syndrome, a rare condition linking cerebrovascular events and livedo reticularis, affects patients with cerebral infarcts and cognitive decline. Treatment outcomes vary, with some experiencing recurrent strokes despite therapy.
Area of Science:
- Neurology
- Vascular Medicine
- Rare Diseases
Context:
- Sneddon's syndrome is a rare neurological disorder characterized by ischemic cerebrovascular events and livedo reticularis.
- Understanding its clinical presentation and progression is crucial for patient management.
Purpose:
- To retrospectively analyze fifteen cases of Sneddon's syndrome.
- To describe the clinical characteristics, neuroimaging findings, arteriopathy, and treatment outcomes in affected individuals.
Summary:
- Fifteen patients (13 female, 2 male, mean age ~38) with Sneddon's syndrome presented with cerebral infarcts, dementia, and white matter changes.
- Cerebral angiography revealed distal arteriopathy in most cases; one patient had antiphospholipid antibodies.
- Treatment with antiplatelet agents or anticoagulants showed variable outcomes, with recurrent infarcts observed in some patients, particularly those not on or discontinuing treatment.
Impact:
- This study highlights the diverse clinical manifestations and neuroimaging findings in Sneddon's syndrome.
- It underscores the importance of identifying underlying arteriopathy and considering treatment strategies to prevent recurrent cerebrovascular events in these patients.
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