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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

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Related Experiment Video

Updated: Jul 11, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

[Lens biomaterials for cataract surgery].

T Amzallag1, J Pynson

  • 1Institut Ophtalmique, Somain.

Journal Francais D'Ophtalmologie
|September 20, 2007
PubMed
Summary

The development of intraocular lenses (IOLs) has seen limited biomaterial innovation since rigid poly-methyl-methacrylate (PMMA) lenses were first used. Current choices like acrylic polymers and silicone elastomers prioritize clinical performance alongside biocompatibility.

Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Polymer Chemistry

Context:

  • The first intraocular lenses (IOLs) utilized rigid poly-methyl-methacrylate (PMMA).
  • Phacoemulsification in the 1970s enabled smaller incisions and material diversification.
  • Despite advancements, the range of IOL biomaterials remains limited to acrylic polymers and silicone elastomers.

Purpose:

  • To review the historical progression and current limitations of biomaterials used in intraocular lens (IOL) technology.
  • To highlight the evolving criteria for biomaterial selection in IOLs, moving beyond simple in vivo tolerance.
  • To emphasize the importance of material properties in conjunction with IOL design for optimal clinical outcomes.

Summary:

  • Intraocular lens (IOL) biomaterial selection has evolved from early poly-methyl-methacrylate (PMMA) to current acrylic and silicone options.

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Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Related Experiment Videos

Last Updated: Jul 11, 2026

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

Modeling Cataract Surgery in Mice
05:19

Modeling Cataract Surgery in Mice

Published on: December 1, 2023

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries
04:59

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

  • Biomaterial choice now critically depends on clinical performance factors such as injectability, optical quality, and long-term intraocular behavior.
  • Physical and chemical characteristics of biomaterials, alongside IOL design, are key to selecting the best lens.

    • Impact:

    • Informs the selection of advanced biomaterials for next-generation intraocular lenses.
    • Contributes to improved patient outcomes through enhanced IOL performance and biocompatibility.
    • Guides future research and development in ophthalmic biomaterials for refractive surgery.