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Published on: July 18, 2017
[Imaging features of xanthogranulomatous pyelonephritis]
L Charrada-Ben Farhat1, W Saïed, N Dali
1Service d'Imagerie et de Radiologie Interventionnelle, Hôpital Mongi Slim --2070 La Marsa, Tunisie.
Diagnosing pseudotumoral xanthogranulomatous pyelonephritis, a rare kidney infection, is challenging. Imaging like CT and MRI can help detect characteristic changes, aiding in diagnosis when combined with clinical findings.
Area of Science:
- Nephrology
- Radiology
- Pathology
Background:
- Pseudotumoral xanthogranulomatous pyelonephritis is a rare chronic renal infection.
- Preoperative diagnosis is often difficult due to non-specific clinical presentations.
Purpose of the Study:
- To evaluate the diagnostic value of various imaging techniques for pseudotumoral xanthogranulomatous pyelonephritis.
- To assess the utility of ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) in diagnosing this condition.
Main Methods:
- Retrospective review of 8 patient cases.
- Analysis of imaging findings from US, CT, and MRI (where available).
- Correlation of imaging findings with clinical and laboratory data.
Main Results:
- US demonstrated non-specific hypoechoic or cystic lesions.
- CT revealed non-specific focal solid or cystic renal masses with peripheral enhancement, often showing obstruction and perirenal involvement.
- MRI, though not used in this cohort, is noted for specific perirenal fat changes suggestive of the diagnosis.
Conclusions:
- Diagnosis can be suspected by combining clinical/laboratory findings with non-specific US/CT features.
- Specific MRI findings of perirenal fat changes are crucial for diagnosis.
- Percutaneous biopsy may be necessary for definitive diagnosis in select cases.
Related Concept Videos
Acute Pyelonephritis I: Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
X-ray Imaging
Imaging Studies III: Computed Tomography
Imaging Studies I: Kidney, Ureter, and Bladder Studies

