Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Organ failure in sepsis.

Herwig Gerlach1, Susanne Toussaint

  • 1Vivantes-Klinikum Neukoelln, Klinik für Anaesthesie, operative Intensivmedizin und Schmerztherapie, Rudower Strasse 48, D-12313 Berlin, Germany. herwig.gerlach@vivantes.de

Current Infectious Disease Reports
|September 21, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Summary of the update to the S3 guideline: Epidemiology, diagnosis and treatment of adult patients with nosocomial pneumonia].

Pneumologie (Stuttgart, Germany)·2025
Same author

[S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2025
Same author

[Epidemiology, diagnosis and treatment of adult patients with nosocomial pneumonia].

Pneumologie (Stuttgart, Germany)·2025
Same author

Key summary of German national guideline for adult patients with nosocomial pneumonia- Update 2024 Funding number at the Federal Joint Committee (G-BA): 01VSF22007.

Infection·2024
Same author

A multifaceted educational intervention improved anti-infectious measures but had no effect on mortality in patients with severe sepsis.

Scientific reports·2022
Same author

Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial.

Critical care (London, England)·2022

Sepsis-induced organ failure significantly impacts patient outcomes. Recent research offers promising advancements in understanding and treating sepsis, including genomic insights and novel therapeutic strategies for organ dysfunction.

Area of Science:

  • Critical Care Medicine
  • Pathophysiology
  • Translational Research

Background:

  • Severe sepsis and septic shock incidence are rising, with mortality rates remaining high despite clinical advancements.
  • Organ failure development is a critical determinant of septic patient prognosis and clinical course.
  • Intensivists' enthusiasm is tempered by the persistent challenge of sepsis management.

Purpose of the Study:

  • To review state-of-the-art publications on sepsis-induced organ failure.
  • To elucidate the impact of organ dysfunction on clinical sepsis management.
  • To highlight recent progress in sepsis research.

Main Methods:

  • Comprehensive literature review of recent sepsis research.
  • Analysis of advancements in definitions, epidemiology, and pathophysiology.

Related Experiment Videos

  • Evaluation of progress in diagnostic and therapeutic approaches.

    • Main Results:

    • Genomic information aids in patient subgroup stratification.
    • Clinical studies expand laboratory diagnostics for sepsis.
    • Basic research illuminates cellular mechanisms of inflammation and organ dysfunction.
    • New insights into pathogenesis and therapeutic strategies for organ failure are emerging.

    Conclusions:

    • Sepsis research is progressing, offering hope for improved patient outcomes.
    • Understanding sepsis-induced organ failure is crucial for clinical practice.
    • Genomic and diagnostic advancements hold potential for personalized sepsis treatment.