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Published on: December 22, 2017
SmedGD: the Schmidtea mediterranea genome database
Sofia M C Robb1, Eric Ross, Alejandro Sánchez Alvarado
1Department of Neurobiology and Anatomy, Howard Hughes Medical Institute, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
The Schmidtea mediterranea Genome Database (SmedGD) centralizes planarian genome data for researchers. This resource supports studies in regeneration, stem cell biology, and comparative genomics.
Area of Science:
- * Developmental Biology
- * Genomics
- * Regenerative Medicine
Background:
- * The planarian Schmidtea mediterranea is a key model organism for regeneration and stem cell research.
- * Advancements in its genome sequencing and annotation highlight the need for accessible data.
- * Existing data is fragmented, hindering comprehensive research efforts.
Purpose of the Study:
- * To create a centralized, web-accessible database for Schmidtea mediterranea genome data.
- * To integrate diverse datasets including genes, ESTs, expression patterns, and phenotypes.
- * To enhance accessibility for the biomedical and planarian research communities.
Main Methods:
- * Development of the Schmidtea mediterranea Genome Database (SmedGD).
- * Integration of genomic data using the Generic Model Organism Database (GMOD) tools.
- * Web portal design for comprehensive data access.
Main Results:
- * SmedGD provides a unified platform for planarian genome information.
- * The database includes annotated genes, ESTs, protein homologies, gene expression, and RNAi phenotypes.
- * Data structure is compatible with other model organism databases.
Conclusions:
- * SmedGD significantly improves access to Schmidtea mediterranea genomic data.
- * The database supports research in regeneration, stem cell biology, and comparative genomics.
- * SmedGD is a valuable resource for planarian researchers and related fields like evolutionary biology.
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