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Related Experiment Video

Updated: Jul 11, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
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[A new flavonoid from Lysimachia foenum-graecum].

Xiang-ri Li1, Zhi-meng Li, Shu-shan Du

  • 1Institute of Scientific Research, Beijing Tong Ren Tang Company Limited, Beijing 100011, China. lixiangri@sina.com

Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|September 22, 2007
PubMed
Summary

Researchers identified a new flavonoid compound, kaempferol-7-O(4"-(E)-p-coumaroyl-)-alpha-L-rhmanopyranosyl)-3-O-beta-D-glucopyranosyl (1-->4)-alpha-L-rhmanopyranosyl (1-->2)-beta-D-glucopyranoside, from the Lysimachia foenum-graecum herb using advanced chromatographic and spectral techniques.

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Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Organic Chemistry

Context:

  • The Lysimachia foenum-graecum herb is a plant species with potential medicinal properties.
  • Understanding the chemical composition of medicinal plants is crucial for drug discovery and development.
  • Flavonoids are a diverse class of natural compounds known for their biological activities.

Purpose:

  • To isolate and characterize the chemical constituents of the Lysimachia foenum-graecum herb.
  • To identify novel compounds with potential pharmacological significance.
  • To elucidate the structure of a newly discovered flavonoid.

Summary:

  • The herb of Lysimachia foenum-graecum was extracted using 70% ethanol.
  • Multi-column chromatography and spectral analysis were employed for isolation and structural determination.
  • A new flavonoid compound, kaempferol-7-O(4"-(E)-p-coumaroyl-)-alpha-L-rhmanopyranosyl)-3-O-beta-D-glucopyranosyl (1-->4)-alpha-L-rhmanopyranosyl (1-->2)-beta-D-glucopyranoside, was successfully identified.

Impact:

  • Discovery of a novel flavonoid compound expands the known chemical diversity of natural products.
  • The identified compound may serve as a lead for developing new therapeutic agents.
  • This research contributes to the phytochemical knowledge base of Lysimachia foenum-graecum.