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Related Experiment Video

Updated: Jul 11, 2026

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse

Published on: December 16, 2022

OEIS complex with major cardiac malformation: a case report.

Prerna Batra¹, Abhijeet Saha, K Y Vilhekar

¹Department of Pediatrics, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra. drprernabatra@yahoo.com

Indian Journal of Pathology & Microbiology

|September 22, 2007

Summary

Omphalocele, exstrophy, imperforate anus, and spinal defects (OEIS Complex) is a rare condition. This case highlights additional cardiac and multisystem anomalies, expanding understanding of this infrequent complex.

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Area of Science:

Medical Genetics
Developmental Biology
Pediatric Surgery

Background:

OEIS Complex (Omphalocele, Exstrophy, Imperforate Anus, Spinal Defects) is a rare congenital disorder.
It typically involves a specific set of anomalies affecting multiple organ systems.

Observation:

This report details a rare case of OEIS Complex with significant additional anomalies.
Major cardiac defects and other multisystem involvements were observed, extending beyond the classic OEIS presentation.

Findings:

The case presented rare, severe multisystem anomalies alongside the core OEIS Complex features.
Literature review confirms the infrequent co-occurrence of these extensive anomalies in OEIS Complex.

Implications:

This case broadens the spectrum of known OEIS Complex manifestations.
Understanding these rare presentations is crucial for accurate prenatal diagnosis and management strategies.