Jove
Visualize
Contact Us

Related Experiment Videos

Placenta in PIH.

M D Kurdukar1, N M Deshpande, S S Shete

  • 1Department of Pathology, Dr. V.M. Govt. Medical College, Solapur.

Indian Journal of Pathology & Microbiology
|September 22, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gonadoblastoma with unusual mixed germ cell overgrowth--a case report.

Indian journal of pathology & microbiology·2006
Same author

Kasabach-Merritt syndrome: a case report.

Indian journal of pathology & microbiology·2006
Same author

Bilateral total renal dysplasia: a case report.

Indian journal of pathology & microbiology·2004
Same author

Early diagnosis of neonatal septicemia by sepsis screen.

Indian journal of pathology & microbiology·2004
Same author

Histopathological study of endometrium in infertility.

Indian journal of pathology & microbiology·2004
Same author

Modeling age x major gene interaction by a variance component approach.

Genetic epidemiology·2002
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Pregnancy Induced Hypertension (PIH) is linked to significant placental villi changes. These placental abnormalities correlate with poorer perinatal outcomes, worsening with increased disease severity.

Area of Science:

  • Obstetrics and Gynecology
  • Pathology
  • Perinatal Medicine

Background:

  • Pregnancy Induced Hypertension (PIH) is a significant complication of pregnancy.
  • Placental villi undergo various changes in PIH, impacting fetal well-being.

Purpose of the Study:

  • To investigate placental villi changes in PIH.
  • To correlate these villous lesions with perinatal outcomes.

Main Methods:

  • Analysis of 49 placentae from PIH patients.
  • Quantification of specific villous lesions, including cytotrophoblastic proliferation, reduced vasculosyncytial membranes, basement membrane thickening, and fibrinoid necrosis.

Main Results:

  • Striking villous changes observed: cytotrophoblastic proliferation, paucity of vasculosyncytial membrane, trophoblastic basement membrane thickening, and fibrinoid necrosis.

Related Experiment Videos

  • These placental lesions were directly proportional to the severity of PIH.
  • Worse perinatal outcomes were associated with advancing grades of PIH.

    • Conclusions:

    • Specific villous histological changes are characteristic of PIH.
    • The severity of these placental changes directly correlates with adverse perinatal outcomes.
    • Histopathological examination of the placenta can aid in assessing PIH severity and predicting perinatal risk.