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Extensive Melanosis Coli, a discolouration from laxative abuse, can mimic ischemic colitis. Correct diagnosis is crucial to avoid unnecessary surgery for this benign condition.

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Area of Science:

  • Gastroenterology
  • Colorectal Surgery

Background:

  • Melanosis Coli is a benign colonic mucosal discolouration.
  • It results from anthraquinone laxative abuse.
  • Extensive cases can be mistaken for ischemic colitis.

Purpose of the Study:

  • To highlight the diagnostic challenge posed by extensive Melanosis Coli.
  • To emphasize Melanosis Coli as a differential diagnosis for ischemic colitis.

Main Methods:

  • Presentation of a case with extensive Melanosis Coli.
  • The condition involved the entire large bowel and appeared gangrenous.
  • Subtotal colectomy was performed based on a presumed diagnosis of ischemic bowel.

Main Results:

  • The patient underwent surgery due to the appearance of the colon.
  • The underlying cause was extensive Melanosis Coli, not ischemia.

Conclusions:

  • Extensive Melanosis Coli can present with features mimicking ischemic colitis.
  • Clinicians must consider Melanosis Coli in the differential diagnosis of ischemic colitis.
  • Accurate diagnosis prevents misidentification and unnecessary surgical intervention.