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Published on: August 18, 2016
Clinical expression of coronary artery ectasia
Serafina Valente1, Chiara Lazzeri, Cristina Giglioli
1Heart and Vessel Department, Azienda Ospedaliero--Universitaria Careggi, University of Florence, School of Medicine, Florence, Italy. seravalente@hotmail.com
Insights
Coronary artery ectasia (CAE) affects 3.6% of patients, predominantly males, and often involves the right coronary artery. Isolated CAE shows a good prognosis, but it is linked to acute coronary syndrome in one-third of cases.
Area of Science:
- Cardiology
- Vascular Medicine
- Diagnostic Imaging
Background:
- Coronary artery ectasia (CAE) is an uncommon finding during cardiac catheterization.
- Understanding its prevalence and clinical associations is crucial for patient management.
Purpose of the Study:
- To retrospectively determine the angiographic prevalence of coronary artery ectasia.
- To investigate the clinical presentation and associations of CAE.
Main Methods:
- Retrospective analysis of 3870 consecutive patients undergoing coronary angiography from January 1999 to June 2001.
- Assessment of CAE prevalence, affected coronary arteries, and association with acute coronary syndromes.
Main Results:
- The prevalence of CAE was 3.6%, predominantly in males (89.2%).
- The right coronary artery was most frequently involved (75%).
- CAE was associated with acute coronary syndrome in 33.1% of cases, often with coexisting stenosis. Isolated CAE was found in 7 patients with ACS, and 66.9% of CAE cases were incidental findings.
Conclusions:
- CAE has an angiographic prevalence of 3.6%, primarily affecting males and the right coronary artery.
- CAE is associated with acute coronary syndrome in approximately one-third of cases.
- Isolated coronary artery ectasia appears to have a favorable prognosis.
Objective:
Coronary artery ectasia (CAE) is an uncommon finding at cardiac catheterisation. Our objective was to retrospectively assess the angiographic prevalence of CAE and its clinical expression.
Methods:
From January 1999 to June 2001, 3870 consecutive patients underwent coronary angiography at our catheterisation laboratory.
Results:
The prevalence of CAE was 3.6%. Most patients were male (89.2%). Type 1 CAE was observed in 20% of patients, type 2 in 11%, type 3 in 43%, and type 4 in 26%. The right coronary artery was most commonly involved (75%). In 55 patients with acute myocardial infarction, CAE within the culprit vessel was found in 32 patients (58.1%): ectasia was associated with stenosis in 29 patients, whereas isolated CAE was observed in only three patients. In 23 patients (41.8%), CAE was detected as a collateral finding in the presence of the culprit occluded, non-ectatic vessel. Overall, in the 109 patients (78%) with acute coronary syndrome, the culprit lesion was found to be related to the ectatic vessel in 46 patients (33.1%): ectasia was associated with stenosis in 39 patients, whereas isolated CAE was observed in only seven patients. In 66.9% CAE was an incidental finding on angiography. At follow-up, three patients with CAE died (2%).
Conclusions:
In our investigation, the angiographic prevalence of CAE was 3.6%. CAE occurred predominantly in males and more often affected the right coronary artery. It was associated with acute coronary syndrome in one third of cases. Isolated CAE was associated with a good prognosis at follow-up.
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