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Impact of dialysis modality on ultrasonographic cardiovascular parameters in elderly patients

Takeyuki Hiramatsu1, Shinji Furuta, Hironobu Kakuta

  • 1Department of Nephrology, Aihoku Hospital, Aichi, Japan. t-hiramatsu@aihoku.jaaikosei.or.jp

Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis
|September 25, 2007
PubMed

Insights

Elderly patients on hemodialysis (HD) showed worsening cardiovascular remodeling over 4 years. Peritoneal dialysis (PD) patients maintained stable cardiac parameters, suggesting PD may be a safer long-term option for elderly individuals with end-stage renal disease.

Area of Science:

  • Nephrology
  • Cardiology
  • Geriatrics

Background:

  • Cardiovascular complications are the leading cause of mortality in end-stage renal disease (ESRD) patients.
  • Ultrasonographic parameters of cardiovascular remodeling can predict mortality in both ESRD patients and the general population.

Purpose of the Study:

  • To compare long-term longitudinal changes in cardiac parameters between elderly patients undergoing peritoneal dialysis (PD) and hemodialysis (HD).

Main Methods:

  • Analysis of 19 HD and 7 PD patients over 75 years old, treated for over 4 years.
  • Comparison of ultrasonographic cardiovascular parameters including left ventricular mass index (LVMI), left ventricular wall thickness (LVWT), and intima media area (IMA) before and after 4 years of dialysis.

Main Results:

  • HD patients exhibited significant increases in LVMI, LVWT, and IMA after 4 years of treatment.
  • PD patients showed no significant changes in these cardiac parameters over the 4-year study period.

Conclusions:

  • Cardiovascular remodeling tends to worsen in elderly patients on HD.
  • Cardiac parameters remain stable in elderly patients on PD, indicating a potentially more favorable long-term cardiovascular profile.

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