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Updated: Jul 11, 2026

Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library
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Genome-wide Screen for miRNA Targets Using the MISSION Target ID Library

Published on: April 6, 2012

The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop

Selvi Ramasamy1, Sekhar Duraisamy, Sergei Barbashov

  • 1Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

Molecular Cell
|September 25, 2007
PubMed
Summary

Mucin 1 (MUC1) protein upregulates galectin-3 expression in human carcinomas by suppressing microRNA miR-322. This interaction is crucial for MUC1 and epidermal growth factor receptor (EGFR) signaling in cancer.

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