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Published on: April 16, 2017
Inherent change in MammoSite applicator three-dimensional geometry over time
Subhakar Mutyala1, Walter Choi, Atif J Khan
1Department of Radiation Oncology, Montefiore Medical Center, Bronx, NY 10467, USA. smutyala@montefiore.org
Radiation Oncology (London, England)
|September 26, 2007
Summary
Accelerated partial breast irradiation using the MammoSite applicator requires symmetry. This study observed three asymmetric cases that spontaneously became symmetric over time without intervention, suggesting potential for self-correction.
Area of Science:
- Oncology
- Radiotherapy
- Medical Devices
Background:
- Accelerated partial breast irradiation (APBI) is a common breast cancer treatment.
- The MammoSite applicator is frequently used for APBI, necessitating precise, symmetric placement for effective radiation delivery.
- Asymmetry in applicator placement can complicate treatment and potentially affect outcomes.
Purpose of the Study:
- To report on cases where the MammoSite applicator placement was initially asymmetric.
- To observe the natural evolution of applicator symmetry over time in these cases.
- To evaluate if spontaneous symmetry can occur without manual adjustment.
Main Methods:
- Review of three patient cases undergoing APBI with the MammoSite applicator.
- Initial assessment of applicator placement for symmetry.
- Longitudinal observation of applicator position without repositioning or manipulation.
Main Results:
- All three cases initially presented with asymmetric MammoSite applicator placement.
- Over time, the applicator in all observed cases spontaneously achieved a symmetric position.
- No intervention or manipulation was required to correct the asymmetry.
Conclusions:
- MammoSite applicator asymmetry may resolve spontaneously over time.
- This finding could have implications for treatment planning and patient management in APBI.
- Further investigation is warranted to understand the mechanisms behind spontaneous symmetry correction.

