Related Experiment Video
Updated: Jul 11, 2026

Isolation and Functional Characterization of Human Ventricular Cardiomyocytes from Fresh Surgical Samples
Published on: April 21, 2014
Alcohol septal ablation versus surgical myectomy: a patient with obstructive HCM
Giovanni La Canna1, Flavio Airoldi, Elvia Capritti
1Echocardiography Unit, Cardiac Surgery Department, Vita-Salute San Raffaele University, Milan, Italy. lacanna.giovanni@hsr.it
Insights
A patient with obstructive hypertrophic cardiomyopathy unsuitable for alcohol septal ablation underwent successful surgical myectomy. Intraoperative echocardiography guided the procedure, offering an alternative treatment for severe symptoms.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Imaging
Background:
- A 42-year-old woman with a 20-year history of symptomatic obstructive hypertrophic cardiomyopathy (oHCM) presented with worsening symptoms despite medical management.
- The patient was referred for consideration of alcohol septal ablation, a minimally invasive treatment option for oHCM.
Observation:
- Comprehensive diagnostic workup included physical examination, electrocardiography, echocardiography (rest-exercise Doppler, 2D, intracoronary myocardial contrast, intraoperative transesophageal, and epicardial), and coronary angiography.
- The patient was determined to be unsuitable for alcohol septal ablation due to specific anatomical or physiological factors.
Findings:
- Surgical myectomy was performed as an alternative therapeutic strategy.
- Intraoperative echocardiography played a crucial role in guiding the surgical myectomy procedure, ensuring precision and effectiveness.
Implications:
- This case highlights the importance of multimodal imaging, particularly intraoperative echocardiography, in guiding surgical interventions for complex cardiac conditions like oHCM.
- Surgical myectomy remains a viable and effective treatment option for carefully selected patients with obstructive hypertrophic cardiomyopathy who are not candidates for septal ablation.
- The successful outcome underscores the multidisciplinary approach required for managing advanced cardiovascular diseases.
Background:
A 42-year-old woman with a 20-year history of obstructive hypertrophic cardiomyopathy was referred for alcohol septal ablation following a worsening of symptoms, which had persisted despite medical treatment.
Investigations:
Physical examination, electrocardiography, rest-exercise Doppler and two-dimensional echocardiography, coronary angiography, intracoronary myocardial contrast echocardiography, and intraoperative transesophageal and epicardial echocardiography.
Diagnosis:
Symptomatic obstructive hypertrophic cardiomyopathy.
Management:
The patient was deemed unsuitable for alcohol septal ablation and underwent surgical myectomy guided by intraoperative echocardiography.
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Mitral Stenosis III: Medical Management
