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Updated: Jul 11, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
[Preoperative treatments of rectal cancers]
J-F Bosset1, F Nguyen, M Bosset
1Service de Radiothérapie-Oncologie, CHU Jean-Minjoz, boulevard Fleming, 25030, Besançon Cedex, France. jean-francois.bosset@ufe-chu.univ-fcomte.fr
Abstract:
Surgery alone is no longer appropriate to the treatment of T3-T4 resecable rectal cancer. Preoperative chemoradiotherapy has recently been approved as the new standard treatment. This approach improves local control with local failure rate raranging now around 6-8%. However, it does not impact on overall survival. It becomes urgent to develop new concepts and a basic research in the understanding of the biological mechanisms that may explain the resistance of the micrometastatic process.
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