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Updated: Jul 11, 2026
06:15
Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Squamous cell carcinoma of cornea
Sudesh K Arya1, Archana Malik, Spinderjeet G Samra
1Ophthalmology, Government Medical College & Hospital, Sector 32A, Chandigarh, 160032, India.
International Ophthalmology
|September 28, 2007
Summary
This case report details an 80-year-old man with isolated squamous cell carcinoma of the cornea. Surgical excision and topical mitomycin C achieved a complete recovery without recurrence.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Squamous cell carcinoma (SCC) of the cornea is a rare ocular malignancy.
- Early diagnosis and appropriate management are crucial for preserving vision and preventing metastasis.
Observation:
- An 80-year-old male presented with decreased vision and a gelatinous corneal mass.
- Ocular examination revealed a limbus-sparing corneal lesion without signs of lymphadenopathy or metastasis.
Findings:
- Histopathology confirmed invasive, well-differentiated squamous cell carcinoma of the cornea.
- Complete surgical excision followed by topical mitomycin C (0.002%) for 4 weeks resulted in no recurrence.
Implications:
- Isolated corneal squamous cell carcinoma, though uncommon, must be considered in the differential diagnosis of corneal masses.
- This case highlights successful management with a combination of surgical resection and adjuvant topical chemotherapy.
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