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Multiple discharging sinuses: an unusual presentation caused by Absidia corymbifera
A J Kindo1, N R Shams, V Srinivasan
1Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Chennai - 600 116, India. anupmalakra@yahoo.com
Indian Journal of Medical Microbiology
|September 29, 2007
Summary
This case report details a diabetic patient with zygomycosis, identified by fungal hyphae in tissue samples. Treatment involved surgery and antifungal medications, leading to a positive outcome.
Area of Science:
- Mycology
- Infectious Diseases
- Dermatology
Background:
- Zygomycosis is a rare, aggressive fungal infection.
- Diabetes mellitus is a significant risk factor for invasive fungal infections.
- Non-healing sinuses can indicate underlying opportunistic infections.
Observation:
- A diabetic patient presented with multiple, non-healing, discharging sinuses.
- Histopathology revealed aseptate fungal hyphae in debrided tissue.
- Potassium hydroxide (KOH) mount confirmed hyaline, aseptate hyphae.
Findings:
- Absidia corymbifera was isolated from tissue cultures.
- The patient had a confirmed diagnosis of zygomycosis.
- The infection presented primarily as cutaneous manifestations.
Implications:
- Early diagnosis and prompt treatment are crucial for managing zygomycosis.
- Multifaceted treatment including surgical debridement and systemic antifungals is effective.
- This case highlights the importance of considering zygomycosis in immunocompromised patients with unusual skin lesions.
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