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Updated: Jul 11, 2026

A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
Late-onset neonatal infections caused by group B Streptococcus associated with viral infection
Josette Raymond1, Jean Baptiste Armengaud, Cécile Lambe
1Service de Bacteriologie, Hôpital Cochin-Saint Vincent de Paul, University Paris V, 27 rue du Faubourg Saint Jacques, 75679, Paris Cedex 14, France. j.raymond@svp.ap-hop-paris.fr
Abstract:
An association between viral infection and late-onset disease caused by group B Streptococcus (GBS), was systematically looked for in neonates hospitalized for fever during a 3 1/2 year period. Five neonates between 5 to 12.5 months of age presented with meningitis (2 cases) or with septicemia (3 cases) caused by GBS. Viral culture, immunofluorescence, and assay of IFNalpha in blood and cerebrospinal fluid were performed. A viral infection was proved in 4 cases and suspected in 1 case (rash and pharyngitis). We speculate that viral infection may provoke late-onset disease in colonized infants with GBS.
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