Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early false-negative diffusion-weighted imaging in brainstem infarction.

Lauren C Frey1, Gene Y Sung, Jody Tanabe

  • 1Department of Neurology, Columbia-Presbyterian Medical Center, New York, NY 10032, USA.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|October 2, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Descriptive Analysis of Retrospective Observational Real-World Evidence of a Monoclonal Anti-Amyloid Therapy Program in a Wide Catchment Specialty Memory Clinic.

Neurology and therapy·2026
Same author

Recruitment feasibility for deep brain stimulation compared to transcranial magnetic stimulation treatment trials for methamphetamine use disorder.

Addictive behaviors reports·2026
Same author

Dose-Escalation Study of Amygdalar Transcranial Focused Ultrasound in Healthy Volunteers.

Neuromodulation : journal of the International Neuromodulation Society·2026
Same author

Dementia Care Research and Psychosocial Factors.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025
Same author

Electrophysiology and Functional Magnetic Resonance Imaging of Cue Craving: Potential Biomarkers for Therapeutic Neuromodulation in Addiction.

Biological psychiatry global open science·2025
Same author

Dose-Escalation Study of Amygdalar Transcranial Focused Ultrasound in Healthy Volunteers.

medRxiv : the preprint server for health sciences·2025
Same journal

Admission Cognitive Function Independently Predicts Discharge Walking Function and Functional Independence After Stroke: A Multicenter Retrospective Cohort Study.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Association Between Race, Ethnicity, and Sex with Prehospital Identification and Outcomes of Patients with Stroke.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Direct Oral Anticoagulants versus Aspirin for Prevention of Overt and Covert Cerebral Infarction: A Meta-Analysis.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Efficacy of Pharyngeal Balloon Muscle Resistance Treatment in Post-Stroke Dysphagia: A Randomized Controlled Trial.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Detection of atrial fibrillation via adhesive single-lead ECG vs. Holter monitoring in embolic stroke of undetermined source: the AVANT-GARDE trial.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Predictive value of the waist-to-height ratio and HbA1c product for incident stroke: a stratified analysis by blood pressure status.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
See all related articles

Diffusion-weighted imaging (DWI) may not always detect early brainstem strokes, even hours after symptom onset. Accurate clinical diagnosis remains crucial for timely thrombolysis treatment in suspected brainstem infarction.

Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • Diffusion-weighted imaging (DWI) is a sensitive tool for detecting acute ischemic stroke.
  • Previous research on DWI for stroke has focused mainly on cortical lesions.
  • Limited data exists on DWI's accuracy and temporal characteristics in brainstem infarction.

Purpose of the Study:

  • To evaluate the utility of DWI in the early detection of brainstem stroke.
  • To report a case of lateral medullary infarction with a false-negative DWI result.

Main Methods:

  • Case report of lateral medullary infarction.
  • Literature review on DWI for brainstem stroke detection.

Main Results:

  • A case of lateral medullary infarction showed a false-negative DWI 16 hours post-symptom onset.

Related Experiment Videos

  • Literature review indicates increasing reports of false-negative DWI in early brainstem stroke detection (0.5-24 hours post-onset).

    • Conclusions:

    • DWI may yield false-negative results in early brainstem infarction.
    • Delayed radiographic confirmation of brainstem stroke necessitates reliance on clinical diagnosis.
    • Prompt clinical diagnosis is vital for initiating thrombolysis and improving outcomes in brainstem stroke.