Related Experiment Video
Updated: Jul 11, 2026

09:10
Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
Published on: February 22, 2020
The association between stroke location and return to work after first stroke
Satoru Saeki1, Kenji Hachisuka
1Department of Rehabilitation Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan. sae@med.uoeh-u.ac.jp
Summary
Stroke survivors
Area of Science:
- Neurology
- Rehabilitation Medicine
- Occupational Health
Background:
- Return to work (RTW) after stroke is influenced by various factors.
- Stroke location's impact on RTW remains under-examined.
Purpose of the Study:
- To investigate the association between stroke location and RTW in working-age adults after their first stroke.
Main Methods:
- Retrospective cohort study of 126 patients younger than 65, working at stroke onset.
- Follow-up questionnaire assessed RTW.
- Cox proportional hazards model analyzed predictors of successful RTW.
Main Results:
- Maximum weakness (HR 3.74), apraxia (HR 10.7), and occupation type (HR 2.11) were significant predictors of RTW.
- Stroke location was not found to be a significant predictor of RTW.
Conclusions:
- Easily measured factors like weakness, apraxia, and occupation are more critical than stroke location for predicting RTW.
- Clinical focus should prioritize these factors for successful return to work strategies.
Related Concept Videos
Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...