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[The etiology of purulent meningoencephalitis in pediatrics. The therapeutic implications]
J Games-Eternod1, F Solórzano-Santos, J López del Prado
1Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social.
Abstract:
In order to know the etiology of purulent meningitis in infant and children, a retrospective study was done; 709 cases of a pediatric infectious disease service were analyzed. Diagnosis was established either by antigen detection (coagglutination) or bacterial culture. In 334/709 (48%) the bacterial agent was identifies. Haemophilus influenzae type b (70%), Streptococcus pneumoniae (14%), Enterobacteriaceae (8%) and Streptococcus sp (6.5%) were the most frequent. According to our results the epidemiologic pattern of purulent meningitis has not changed. A therapeutic approach is suggested.
Insights
The etiology of bacterial meningitis in children was studied, identifying Haemophilus influenzae type b as the most common cause. The study suggests the epidemiologic pattern remains unchanged, recommending a therapeutic approach.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Epidemiology
Context:
- Purulent meningitis is a significant cause of morbidity and mortality in infants and children.
- Understanding the causative agents is crucial for effective treatment and prevention strategies.
Purpose:
- To determine the etiology of purulent meningitis in pediatric patients.
- To analyze the frequency of bacterial pathogens responsible for meningitis in children.
- To inform therapeutic approaches based on current epidemiological patterns.
Summary:
- A retrospective analysis of 709 pediatric cases of purulent meningitis was conducted.
- Bacterial agents were identified in 48% of cases, with Haemophilus influenzae type b (70%) being the most prevalent.
- Streptococcus pneumoniae, Enterobacteriaceae, and Streptococcus sp. were also significant contributors.
Impact:
- The findings indicate a persistent epidemiological pattern of purulent meningitis in children.
- This study provides essential data for guiding clinical management and public health interventions.
- Results support the need for continued surveillance and potential adjustments in therapeutic strategies.