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Published on: January 11, 2016
Visual evoked responses to pattern reversal in children.
1Department of Physiology University College of Medical Sciences, Delhi.
Indian Journal of Physiology and Pharmacology
|July 1, 1991
Summary
Pattern reversal evoked potentials (PREPs) provide normative visual pathway data in children aged 4-15. This study found no significant differences in PREPs between genders or eyes, establishing baseline visual function in healthy children.
Area of Science:
- Neuroscience
- Ophthalmology
- Pediatric Neurology
Background:
- Establishing normative visual evoked potential (VEP) data is crucial for diagnosing visual pathway disorders in children.
- Pattern reversal evoked potentials (PREPs) are sensitive indicators of visual pathway function.
Purpose of the Study:
- To establish normative data for pattern reversal evoked potentials (PREPs) in school-aged children.
- To investigate potential differences in PREPs based on gender and eye laterality.
Main Methods:
- Utilized Ag/AgCl electrodes at O1-A1 and O2-A2 scalp sites for recording.
- Administered 256 pattern reversal stimuli (32' check size, 1 Hz rate) to each eye.
- Averaged and analyzed evoked responses using a computer system to determine VEP component latencies and P1 amplitudes.
Main Results:
- Collected and reported normative data for visual evoked potentials in children aged 4-15 years.
- Analyzed data separately for right and left eyes, and for boys and girls.
- Found no statistically significant differences in VEP parameters between genders or between the eyes.
Conclusions:
- The study provides valuable normative VEP data for pediatric populations.
- Gender and eye laterality do not appear to influence pattern reversal evoked potentials in children within the studied age range.
- These findings support the use of PREPs as a reliable tool for assessing visual function in children without considering gender or eye-specific variations.

