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Updated: Jul 11, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Juvenile rheumatic mitral stenosis with multiple ventricular septal defects
Cheemalapati Sai Krishna1, Vedangi Ramesh Babu, Kanteti Ram Mohan
1Department of Cardiothoracic and Vascular Surgery, Apollo Heart Institute, Waltair Main Road, Visakhapatnam 530002, Andhra Pradesh, India. csaikrishna@yahoo.com
Congenital heart disease (CHD) and rheumatic heart disease (RHD) rarely coexist. This case report details an unusual co-occurrence in a child, emphasizing the importance of thorough cardiac evaluations.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Rheumatology
Background:
- Congenital heart disease (CHD) arises during embryonic development.
- Rheumatic heart disease (RHD) results from immune responses to streptococcal infections.
- These conditions typically have distinct origins and presentations.
Observation:
- A 7-year-old girl presented with multiple ventricular septal defects and severe pulmonary arterial hypertension.
- She also had coexisting rheumatic mitral stenosis.
- This represents an uncommon clinical association.
Findings:
- The patient exhibited both congenital and acquired valvular heart abnormalities.
- The severe pulmonary arterial hypertension was linked to the mitral stenosis.
- This case underscores a rare overlap between CHD and RHD.
Implications:
- Clinicians should consider the possibility of coexisting rheumatic heart disease in children with late-presenting congenital heart defects.
- Comprehensive diagnostic approaches are crucial for accurate diagnosis and management.
- This finding may influence diagnostic guidelines for pediatric heart conditions.
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