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Updated: Jul 11, 2026

Isolation of Retinal Stem Cells from the Mouse Eye
Published on: September 11, 2010
Retinal stem cells: promising candidates for retina transplantation
Meta W Djojosubroto1, Yvan Arsenijevic
1Unit of Gene Therapy & Stem Cell Biology, Jules-Gonin Eye Hospital, Ophthalmology Department, University of Lausanne, 15 Avenue de France, 1004, Lausanne, Switzerland.
Abstract:
Stem cell transplantation is widely considered as a promising therapeutic approach for photoreceptor degeneration, one of the major causes of blindness. In this review, we focus on the biology of retinal stem cells (RSCs) and progenitor cells (RPCs) isolated from fetal, postnatal, and adult animals, with emphasis on those from rodents and humans. We discuss the origin of RSCs/RPCs, the markers expressed by these cells and the conditions for the isolation, culture, and differentiation of these cells in vitro or in vivo by induction with exogenous stimulation.
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