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Related Concept Videos

Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...

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Related Experiment Video

Updated: Jul 11, 2026

Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography
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Published on: January 7, 2015

Dermal fillers for facial soft tissue augmentation.

Sarosh F Dastoor1, Carl E Misch, Hom-Lay Wang

  • 1Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan 1011 North University Avenue, Ann Arbor, MI 48109, USA.

The Journal of Oral Implantology
|October 5, 2007
PubMed
Summary

Dermal fillers offer solutions for facial aging and defects, enhancing both dental and overall facial aesthetics. This review covers wrinkle causes, filler history, methods, materials, and controversies for soft tissue augmentation.

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Published on: July 11, 2025

Area of Science:

  • Aesthetic medicine
  • Dermatology
  • Cosmetic surgery

Background:

  • Growing patient demand for improved dental and facial aesthetics.
  • Facial aging, gravity, and trauma contribute to aesthetic defects.
  • Soft tissue augmentation is a key treatment modality.

Purpose of the Study:

  • To review the pathogenesis of facial wrinkles.
  • To explore the history, techniques, and materials of dermal fillers.
  • To discuss complications and clinical controversies in soft tissue augmentation.

Main Methods:

  • Literature review on facial wrinkles and dermal fillers.
  • Analysis of historical and current techniques.
  • Examination of various filler materials and their properties.

Main Results:

  • Facial wrinkles result from aging, gravity, and environmental factors.
  • Dermal fillers are versatile for correcting wrinkles, lip thinning, and asymmetry.
  • A range of materials exist, each with specific indications and risks.

Conclusions:

  • Dermal fillers are integral to modern aesthetic practice.
  • Understanding filler science is crucial for optimal outcomes.
  • Ongoing research addresses safety and efficacy in soft tissue augmentation.