Evaluation of left atrial size on transoesophageal echocardiography: what is the best measure?
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Updated: Jul 11, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Suzanne Eshoo1, David L Ross, Liza Thomas
1University of Sydney, Westmead Hospital, Sydney, Australia. suzannee@westgate.wh.usyd.edu.au
Background:
There is no well established measurement of left atrial (LA) size on transoesophageal echocardiography (TOE). We sought to determine which measurement on TOE would best correlate with LA size obtained from transthoracic echocardiography (TTE).
Methods:
LA diameter (LAD) and volume (LAV) on TOE were compared to TTE measurements from 57 patients. The transthoracic examination was performed just prior to the TOE under 'similar clinical conditions'. LAD was obtained by M-mode and LAV was estimated by area-length method, M-mode derived LAD and the Simpson's method on TOE and compared to LAV estimated by the Simpson's method on transthoracic examination.
Results:
Despite LAD and LAV being underestimated on TOE, good correlations were present between LAD (r=0.85; p=0.001), area-length LAV (r=0.72; p=0.001) and Simpson's LAV (r=0.8; p=0.001). Bland Altman analysis for comparison of LAD between transoesophageal and transthoracic measurements demonstrated a mean difference of -2mm. Simpson's LAV on TOE gave the best estimation of LAV from TTE with a mean difference of -6 ml as compared to -10 ml by area-length LAV in the cohort studied.
Conclusion:
Both left atrial diameter and volume are underestimated on TOE. The best measure with the least under-estimation of LA volume on transoesophageal examination as compared to TTE measures is obtained from Simpson's biplane estimation of LA volume.

