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Published on: April 2, 2021
Ophthalmological problems associated with preterm birth
A R O'Connor1, C M Wilson, A R Fielder
1Division of Orthoptics, University of Liverpool, Liverpool, UK.
Insights
Preterm infants face increased risks of serious eye conditions like retinopathy of prematurity and vision impairment. These visual deficits impact overall development, highlighting the lifelong challenges of premature birth.
Area of Science:
- Ophthalmology
- Neonatology
- Developmental Pediatrics
Background:
- Improved survival rates for preterm infants have increased the prevalence of long-term ophthalmic issues.
- Preterm birth significantly impacts the developing ocular system, leading to diverse visual problems.
- Retinopathy of prematurity is a major concern, potentially causing severe vision loss.
Purpose of the Study:
- To review normal ocular development and its disruption in preterm infants.
- To examine the incidence and visual consequences of various ophthalmic deficits in preterm populations.
- To compare visual outcomes in preterm and term infants.
Main Methods:
- Review of existing literature on ocular development and preterm-related ophthalmic conditions.
- Analysis of studies comparing visual function in preterm versus term infants.
- Discussion of causal and resultant factors in ophthalmic deficits.
Main Results:
- Preterm infants exhibit higher rates of refractive errors, strabismus, and cerebral vision impairment.
- These visual impairments significantly affect overall visual function and development.
- Ophthalmic deficits in preterm infants are multifactorial, often with intertwined causes.
Conclusions:
- Children born prematurely experience a higher incidence of all types of ophthalmic deficits.
- The visual challenges faced by preterm infants have lasting impacts on their development.
- Preterm infants require comprehensive, long-term ophthalmic care due to lifelong visual compromises.
Abstract:
As survival of preterm infants improves, the long-term care of consequent ophthalmic problems is an expanding field. Preterm birth can inflict a host of challenges on the developing ocular system, resulting in the visual manifestations of varied significance and pathological scope. The ophthalmic condition most commonly associated with preterm birth is retinopathy of prematurity, which has the potential to result in devastating vision loss. However, the visual compromise from increased incidence of refractive errors, strabismus, and cerebral vision impairment has significant impact on visual function, which also has influence on other developmental aspects including psychological and educational. In this review, the normal ocular development is discussed, aiming to exemplify the impact of early exteriorisation on one of the more naive organs of prematurity. This is then related to the incidence and visual consequences of many types of deficit, including refractive error, strabismus, and loss of visual function in preterm populations, with comparisons to term infant studies. Often these conditions are linked with causal and resultant factors being impossible to segregate, but the common factor of increased rates of all types of ophthalmic deficits demonstrates that children born prematurely are indeed premature for life.
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