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Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Ethics in Research

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.

Ethical Issues

Ethical Issues

Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:

Maintenance of the ES Cell State

Maintenance of the ES Cell State

The cells of the blastocyst inner cell mass only remain pluripotent for a short time. This state of pluripotency and self-renewal can be maintained in embryonic stem (ES) cell culture by adding specific chemicals or growth factors to ensure the cells can continue dividing and later differentiate into different cell types. In some cases, the cells are grown on a feeder layer of differentiated cells, which provides the growth factors and extracellular matrix components necessary for stem cell...

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Related Experiment Video

Updated: Jul 11, 2026

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

Stem cell research ethics: consensus statement on emerging issues.

Timothy Caulfield¹, Ubaka Ogbogu, Erin Nelson

¹Health Law Institute, Faculty of Law, School of Public Health, University of Alberta, Edmonton AB.

Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'Obstetrique Et Gynecologie Du Canada : JOGC

|October 5, 2007

Summary

This consensus statement addresses ethical, legal, and social issues in human embryonic stem cell (hESC) research in Canada. It offers recommendations for Canadian policymakers on key issues like informed consent and embryo use.

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Area of Science:

Focuses on the ethical, legal, and social dimensions of human embryonic stem cell (hESC) research.

Background:

An international interdisciplinary group of experts and Canadian policymakers convened to discuss emerging issues.
Consultations included stakeholders in regulations, stem cell research, and research ethics.

Framework:

Developed through background paper distribution and an international workshop in Montreal (February 2007).
Aimed to debate recommendations for policy development.

Implementation:

Recommendations target immediate relevance for Canadian policymakers.
Key areas include informed consent for hESC research and the use of fresh embryos.

Implications:

Addresses management of conflicts of interest in research.
Considers the relevance of public opinion research for policy-making in stem cell science.