Related Experiment Videos
An outreach program improved osteoporosis management after a fracture
Adrianne C Feldstein1, William M Vollmer, David H Smith
1Northwest Permanente, Portland, Oregon, USA. adrianne.c.feldstein@kpchr.org
Journal of the American Geriatrics Society
|October 5, 2007
Summary
An outreach program significantly improved osteoporosis management after fractures in older women. This intervention enhanced secondary prevention by increasing bone density testing and treatment rates.
Area of Science:
- Gerontology
- Public Health
- Health Services Research
Background:
- Osteoporosis management after fracture is crucial for secondary prevention.
- Previous osteoporosis management rates in the studied population were suboptimal.
- Effective interventions are needed to improve post-fracture osteoporosis care.
Purpose of the Study:
- To evaluate an intervention aimed at improving osteoporosis management after fracture.
- To assess the impact of outreach and incentives on clinician and patient engagement.
- To determine the effectiveness of the intervention in increasing bone mineral density (BMD) testing and osteoporosis treatment.
Main Methods:
- Longitudinal retrospective cohort study in a large health maintenance organization (HMO).
- Inclusion of female HMO members aged 67+ with qualifying fractures and no prior BMD or treatment.
- Intervention phases included clinician/patient outreach (Phase 1) and added incentives (Phase 2).
- Primary outcome: osteoporosis management (BMD test or medication) within 6 months post-fracture.
Main Results:
- Baseline osteoporosis management was 13.4%; no significant time trend pre-intervention.
- Post-intervention, management probability increased by 3.1% every 2 months.
- Overall management probability rose to 44.0% by study end (20 months).
- Improvement varied by clinic; less effective in patients with dementia.
Conclusions:
- An outreach program effectively improved osteoporosis management post-fracture.
- The intervention demonstrated substantial potential for secondary osteoporosis prevention.
- Targeted strategies may be needed for high-risk subgroups like patients with dementia.
Related Concept Videos
Fractures: Bone Repair
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Osteoclasts in Bone Remodeling
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone Remodeling
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Remodeling and Repair
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Role of Vitamins in Maintaining Bone Health
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...