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A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
Published on: August 16, 2017
Using MeSH to search for alternatives to the use of animals in research
Marina Chilov1, Konstantina Matsoukas, Nighat Ispahany
1Augustus C. Long Health Sciences Library of Columbia University, 701 West 168th Street, New York, NY 10032, USA. mz84@columbia.edu
Abstract:
Searching for alternatives to using animals in research is not a standard service currently offered by most medical research libraries. The goal of this article is to demystify this type of expert search for medical librarians and to do so using a language they know well, that of the Medical Subject Headings (MeSH) thesaurus. An attempt is made in this paper to discuss possible search strategies and to include examples of recommended approaches to searching-all in the context of the 3Rs of alternatives: Replacement, Refinement, and Reduction.
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