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Published on: September 20, 2019
[Errors for delivery medications through gastrostomy devices: study of 109 children]
L Pélissier-Delour1, L Michaud, M Pourrat
1Unité de gastroentérologie, d'hépatologie et de nutrition, hôpital Jeanne-de-Flandre, CHRU de Lille, université de Lille-II, 59037 Lille, France.
Insights
Drug administration errors are common in children using gastrostomy tubes, particularly in institutionalized or neurologically impaired individuals. Improving medication delivery through gastrostomy devices is crucial for patient safety.
Area of Science:
- Pediatric Gastroenterology
- Clinical Pharmacy
- Patient Safety
Context:
- Gastrostomy tubes are widely used for medication delivery in children.
- Current practices for drug administration via gastrostomy devices lack standardization.
- Potential risks associated with improper drug administration are not well understood.
Purpose:
- To evaluate drug administration methods used with gastrostomy devices in pediatric patients.
- To identify and classify errors occurring during medication delivery through gastrostomy tubes.
- To explore factors influencing the frequency of these administration errors.
Summary:
- A study of 109 children found frequent errors in drug administration via gastrostomy tubes, including issues with drug formulation (galenic), preparation, physico-chemical interactions, and tube flushing.
- Institutionalized children experienced significantly more errors (78%) compared to those at home (25%).
- Neurologically impaired children showed a higher incidence of galenic errors (57%).
Impact:
- Highlights the prevalence of potentially dangerous medication errors in pediatric gastrostomy tube use.
- Identifies specific error types and risk factors, such as institutionalization and neurological impairment.
- Underscores the need for standardized protocols and improved caregiver education for safer drug administration.
Unlabelled:
Gastrostomy is frequently used in clinical practice for drug administration. However modalities of drug administration via a gastrostomy device have been poorly studied and remain uncodified.
Aim:
To assess the mode of administration of drugs as well as errors associated with the use of a gastrostomy devices for drug delivery in children.
Patients And Methods:
Mode of administration of drugs was studied in 109 children (mean age 8.4+/-5.5 years, 72% neurologically impaired, 41% institutionalized children). A questionnaire was filled in by parents and/or caregivers. Errors of administration were classified as follows: galenic, due to preparation, physico-chemical interaction, lack of flushing the tube. Factors influencing the occurrence of errors were studied: living at home or in an institution, underlying disease, number of drugs administered via gastrostomy device.
Results:
Errors were frequently observed: galenic (47%), due to preparation (42%), physico-chemical interaction (51%), lack of flushing (10%). Errors occurred more frequently in institutionalized children compared to children living at home (78 versus 25%, P<0.0005). Galenic errors were more frequent in neurologically impaired children (57 versus 30%, P<0.005).
Conclusion:
Many medications are administrated via gastrostomy tube in children. Errors are frequently observed and potentially dangerous.
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