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Updated: Jul 11, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Fresh-frozen allograft anterior cruciate ligament reconstruction
Matthew L Busam1, John-Paul H Rue, Bernard R Bach
1Cincinnati Sports Medicine Research and Education Foundation, Cincinnati, OH, USA.
Abstract:
Reconstruction of the anterior cruciate ligament provides consistently good to excellent results allowing return to work and sport. Allograft tissue is an alternative to autografts when appropriate donor tissue is not available or its use is not advisable for other reasons. The technique and results for allograft use are similar to those for autograft, making its use appropriate in a variety of clinical scenarios. This article reviews the indications for allograft ACL reconstruction, graft options, and technique for allograft use.
