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Association between sleep duration and hemoglobin A1c level.
Hiromi Nakajima1, Yoshitaka Kaneita, Eise Yokoyama
1Division of Public Health, Department of Social Medicine, Nihon University, Tokyo, Japan.
Sleep Medicine
|October 9, 2007
Summary
Both short and long sleep durations are linked to higher hemoglobin A1c (HbA1c) levels. Maintaining an appropriate sleep duration may be crucial for managing glucose tolerance and preventing diabetes.
Area of Science:
- Endocrinology
- Sleep Medicine
- Public Health
Background:
- The relationship between sleep habits and glycemic control, specifically hemoglobin A1c (HbA1c) levels, requires further investigation.
- Understanding these associations is vital for developing strategies to manage glucose tolerance disorders.
Purpose of the Study:
- To examine the association between sleep duration and hemoglobin A1c (HbA1c) levels in a community-based population.
- To identify potential optimal sleep durations for individuals with impaired glucose tolerance.
Main Methods:
- A cross-sectional study involving 1062 residents in a rural Japanese community.
- Data collected via self-administered questionnaires, with measurements of fasting plasma glucose and HbA1c levels.
- Logistic regression analyses were used to assess the association between sleep duration and high HbA1c levels (≥6.5%).
Main Results:
- A significant U-shaped association was observed between sleep duration and HbA1c levels.
- Individuals reporting both short and long sleep durations exhibited significantly higher prevalence of elevated HbA1c levels (p<0.01).
- Logistic regression confirmed a significant association between high HbA1c levels and both short and long sleep durations, with high adjusted odds ratios.
Conclusions:
- Sleep duration demonstrates a U-shaped relationship with HbA1c levels, indicating that both extremes are detrimental.
- An appropriate sleep duration range may be important for individuals with glucose tolerance disorders.
- These findings suggest potential implications for the prevention and management of diabetes mellitus through sleep habit modification.
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