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Related Experiment Video

Updated: Jul 11, 2026

Assessing Activity-based Anorexia in Mice

Assessing Activity-based Anorexia in Mice

Published on: May 14, 2018

PANDAS anorexia nervosa--endangered, extinct or nonexistent?

Frances Puxley¹, Marie Midtsund, Alina Iosif

¹Regional Eating Disorders Service, Ulleval University Hospital, Oslo, Norway.

The International Journal of Eating Disorders

|October 9, 2007

Summary

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infection-Anxiety (PANDAS-AN) shows limited evidence due to diagnostic challenges. Further research with clear criteria is crucial for understanding and treating these conditions.

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Area of Science:

Neuroscience
Pediatric Psychiatry
Infectious Diseases

Background:

Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infection (PANDAS) is established for certain tic and obsessive-compulsive disorders.
PANDAS-AN, a related condition, has recently been described, prompting a critical review of its concept.

Observation:

Evidence for PANDAS-AN exists but is hampered by methodological issues.
Key limitations include low prevalence, unclear diagnostic criteria, and non-specific diagnostic tests.

Findings:

The current evidence base for PANDAS-AN is limited.
Innovative treatments show potential but require rigorous evaluation.

Implications:

Further research is essential for PANDAS-AN.
Developing clear and consistent diagnostic criteria is paramount.
This research may enhance understanding of anxiety disorder pathogenesis and lead to more effective treatments.