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Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
Published on: November 5, 2019
Sickle cell trait.
1University of Oklahoma, Norman, OK, USA. Reichner1@cox.net
Journal of Sport Rehabilitation
|October 10, 2007
Summary
Athletes with sickle cell trait face risks during intense exercise. Exertional sickling can cause collapse, but screening and precautions help prevent this medical emergency.
Area of Science:
- Exercise Physiology
- Sports Medicine
- Hematology
Background:
- Sickle cell trait poses a significant risk to athletes, with exertional sickling causing fatalities.
- Intense exercise can trigger sickling of red blood cells, leading to blood vessel obstruction.
Purpose of the Study:
- To explain the physiological mechanisms of exertional sickling in athletes.
- To highlight the dangers and distinguish exertional sickling syndrome from heat illnesses.
Main Methods:
- Review of exercise-physiology research on red blood cell behavior during exertion.
- Analysis of clinical case studies and metabolic consequences of exertional sickling.
Main Results:
- Sickle red blood cells can accumulate rapidly during intense exercise, causing blood vessel logjams.
- Exertional sickling can lead to ischemic rhabdomyolysis and life-threatening complications.
- Factors like heat, dehydration, altitude, and asthma exacerbate sickling risk.
Conclusions:
- Exertional sickling is a distinct medical emergency requiring immediate recognition.
- Screening for sickle cell trait and implementing preventative measures are crucial.
- With proper precautions, athletes with sickle cell trait can safely participate in sports.
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