[The course of chronic kidney failure during acetate and bicarbonate hemodialysis]

In patients with chronic renal failure (CRF) given acetate (n = 55) and bicarbonate (n = 45) hemodialysis, the dynamics of the progress of uremia symptoms estimated in marks, the index of the lean body weight, the rate of urea generation, the magnitudes of the dialysis indices according to creatinine and urea, TACur and TADur were studied on a monthly basis for many years. The actual survival rates were calculated. It has been demonstrated that as compared to acetate hemodialysis, in patients on bicarbonate hemodialysis, the progress of uremia symptoms is significantly decelerated (p less than 0.05) and hypercatabolism of proteins is decreased by the 4th year of the observation period. This enhances the patients' medical rehabilitation and noticeably increases the actual survival of the patients (p less than 0.001). Advantages of the treatment of CRF patients by bicarbonate hemodialysis are under discussion.