Related Experiment Video
Updated: Jul 11, 2026

Structure-Based Simulation and Sampling of Transcription Factor Protein Movements along DNA from Atomic-Scale Stepping to Coarse-Grained Diffusion
Published on: March 1, 2022
Simple combined model for nonlinear excitations in DNA
D L Hien1, N T Nhan, V Thanh Ngo
1Institute of Physics and Electronics, P. O. Box 429, Boho, Hanoi 10000, Vietnam.
Abstract:
We propose a simple model for DNA denaturation bases on the pendulum model of Englander [Proc. Natl. Acad. Sci. U.S.A. 77, 7222 (1980)] and the microscopic model of Peyrard and Bishop [Phys. Rev. Lett. 62, 2755 (1989)], so-called "combined model." The main parameters of our model are the coupling constant k along each strand, the mean stretching y* of the hydrogen bonds, the ratio of the damping constant and driven force gamma/F. We show that both the length L of unpaired bases and the velocity v of kinks depend on not only the coupling constant k but also the temperature T. Our results are in good agreement with previous works.
Related Concept Videos
DNA as a Genetic Template
Nucleosome Remodeling
Nucleosome remodeling complex
Eukaryotic cells have specialized enzymes called ATP-dependent nucleosome remodeling enzymes. These enzymes...
The DNA Helix
The DNA Helix
DNA Topoisomerases
Types and Mechanism of action
Topoisomerases are divided into two main types. Type I...
Homologous Recombination

