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Updated: Jul 11, 2026

Lipid-Protein Membrane Structure-Function Characterization using Droplet Interface Bilayers
Published on: June 12, 2026
Distinct water species confined at the interface of a phospholipid membrane
Victor V Volkov1, D Jason Palmer, Roberto Righini
1European Laboratory for Nonlinear Spectroscopy (LENS), University of Florence, Via Nello Carrara 1, 50019 Sesto Fiorentino, Italy.
Abstract:
The physics of confined water has stimulated extensive research in recent years, in particular, regarding the role of hydrogen bonding as a significant factor in the observed dynamics. In this work, two-dimensional infrared spectroscopy was employed to investigate the response of the OH moiety of water in phospholipid membrane samples. The results show strong evidence for three distinct hydrogen bonding motifs (H2O with zero, one, or both OH moieties hydrogen bonded), whose relative proportions at the membrane interface are estimated.
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