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Related Concept Videos

Proteomics01:33

Proteomics

9.7K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
9.7K
Oral Cavity01:11

Oral Cavity

3.1K
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
3.1K
Oral Hypoglycemic Agents: Glinides01:06

Oral Hypoglycemic Agents: Glinides

655
Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively...
655
Psychosexual Stages of Personality: Oral01:16

Psychosexual Stages of Personality: Oral

3.0K
The oral stage is the initial phase of Sigmund Freud's theory of psychosexual development, occurring from birth to approximately 12 to 18 months. During this period, the infant's mouth serves as the primary source of pleasure, with actions such as sucking, chewing, biting, and drinking playing a crucial role in reducing tension. These activities are essential not only for nourishment but also for the infant's psychological and emotional satisfaction.
Weaning, typically occurring...
3.0K
Assessing Body Temperature - Oral01:14

Assessing Body Temperature - Oral

1.6K
Here are the steps to accurately measure oral temperature using an electronic thermometer:
Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...
1.6K
Oral Hypoglycemic Agents: Sulfonylureas01:17

Oral Hypoglycemic Agents: Sulfonylureas

1.0K
Sulfonylureas are oral hypoglycemic agents utilized in treating type 2 diabetes. They are characterized by their unique sulfonylurea chemical structure. The family of sulfonylureas is divided into generations. First-generation sulfonylureas, including tolbutamide (Orinase), chlorpropamide (Diabinese), and tolazamide (Tolinase), trigger insulin release from pancreatic β cells and enhance peripheral tissues' insulin sensitivity. The second-generation members, such as glipizide...
1.0K

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Updated: Jan 30, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
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Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

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Oral cancer proteomics.

Shen Hu1, David T Wong

  • 1School of Dentistry, UCLA School of Dentistry, Dental Research Institute, Los Angeles, CA 90095-1668, USA. shenhu@ucla.edu

Current Opinion in Molecular Therapeutics
|October 13, 2007
PubMed
Summary
This summary is machine-generated.

Proteomics offers new ways to study oral cancer. This technology helps find cancer markers, understand disease causes, and develop better treatments for early detection and patient recovery.

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Preparation of Mitochondria from Ovarian Cancer Tissues and Control Ovarian Tissues for Quantitative Proteomics Analysis
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Area of Science:

  • Oral cancer research
  • Proteomics
  • Molecular profiling

Background:

  • Oral cancer remains a significant global health challenge.
  • Traditional research methods have limitations in understanding complex cancer biology.
  • Proteomics provides a powerful lens for molecular investigation.

Purpose of the Study:

  • To review advancements in oral cancer proteomics.
  • To discuss the potential applications of proteomics in oral cancer research.
  • To highlight how proteomics can improve diagnosis, treatment, and patient outcomes.

Main Methods:

  • Review of recent literature on oral cancer proteomics.
  • Analysis of current and emerging proteomics technologies.
  • Discussion of translational applications in clinical oncology.

Main Results:

  • Proteomics enables discovery of sensitive and specific biomarkers for oral cancer diagnosis and prognosis.
  • It aids in elucidating molecular mechanisms and signaling pathways driving oral cancer.
  • Proteomics can identify novel therapeutic targets and assess drug effectiveness.

Conclusions:

  • Proteomics is a rapidly developing field with vast potential in oral cancer research.
  • Applications include early detection, personalized treatment strategies, and monitoring treatment response.
  • This technology promises to significantly improve the management and outcomes for oral cancer patients.