Improving the drug selection and development process for combination devices
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Published on: January 19, 2019
Maggie A Z Hupcey1, Sean Ekins
1PA Consulting Group, 600 College Road East, Suite 1120, Princeton, NJ 08540, USA. maggie.hupcey@paconsulting.com
Abstract:
Combination devices are at the interface of both pharmaceutical and medical device research. While there have been several notable successes in bringing combination devices to market there are drug selection criteria that both the pharmaceutical and medical device companies need to consider. A successful combination device creates a product that has efficacy greater than the sum of the parts. However, failure to address some aspects of the drug or biologic properties in enough detail could result in a suboptimal product, creating a challenging legacy for future iterations. This review addresses the many dimensions including opportunities and challenges of combination device development from both the device and pharmaceutical perspectives.
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