Related Experiment Video
Updated: Jul 10, 2026

A Conditioned Place Preference Protocol for Measuring Incubation of Craving in Rats
Published on: November 6, 2018
Rooming-in compared with standard care for newborns of mothers using methadone or heroin
Ronald R Abrahams1, S Ann Kelly, Sarah Payne
1UBC Department of Health Care and Epidemiology, 5804 Fairview Ave, Vancouver, BC.
Objective:
To evaluate the effect of rooming-in (rather than standard nursery care) on the incidence and severity of neonatal abstinence syndrome among opioid-exposed newborns and on the proportion of mothers who retain custody of their babies at hospital discharge.
Design:
Retrospective cohort study.
Setting:
Lower mainland in southwestern British Columbia.
Participants:
We selected 32 women in the city of Vancouver known to have used heroin or methadone during pregnancy between October 2001 and December 2002. Comparison groups were a historical cohort of 38 women in Vancouver and a concurrent cohort of 36 women cared for in a neighbouring community hospital.
Main Outcome Measures:
Need for treatment with morphine, number of days of treatment with morphine, and whether babies were discharged in the custody of their mothers.
Results:
Rooming-in was associated with a significant decrease in need for treatment of neonatal abstinence syndrome compared with the historical cohort (adjusted relative risk [RR] 0.40, 95% confidence interval [CI] 0.20 to 0.78) and the concurrent cohort (adjusted RR 0.39, 95% CI 0.20 to 0.75). Rooming-in was also associated with shorter newborn length of stay in hospital compared with both comparison groups. Newborns who roomed in at BC Women's Hospital were significantly more likely to be discharged in the custody of their mothers than babies in the historical cohort (RR 2.23, 95% CI 1.43 to 3.98) or the concurrent cohort (RR 1.52, 95% CI 1.15 to 2.53) were.
Conclusion:
Rooming-in might ease opioid-exposed newborns' transition to extrauterine life and promote more effective mothering.
Related Concept Videos
Factors Affecting Drug Response: Overview
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Restorative Care
Pharmacokinetics in Pediatric Patients: Drug Excretion
Drug Dosing: Infants and Children
Specialized Care Centers and Settings-II
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...

