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Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...

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Articles linked to this work by shared authors, journal, and citation graph.

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[Extrahepatic manifestations of infection with hepatitis C virus].

Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru·2009
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Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
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[Hepatitis c and pregnancy].

Waldo O García Ferrera1, Josefina López Menéndez

  • 1Departamento de Gastroenterología, Sección de Hepatologia, Hospital Universitario.

Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru
|October 16, 2007
PubMed
Summary

Pregnancy significantly alters human physiology, potentially leading to liver diseases such as hyperemesis gravidarum and HELLP syndrome. Viral hepatitis, particularly Hepatitis E and Herpes Simplex Virus, are primary causes of jaundice in pregnant individuals.

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Area of Science:

  • Obstetrics and Gynecology
  • Hepatology
  • Maternal-Fetal Medicine

Context:

  • Pregnancy induces profound physiological changes impacting maternal health.
  • Liver diseases during pregnancy include hyperemesis gravidarum, HELLP syndrome, cholestasis, and acute fatty liver.
  • Viral hepatitis is a leading cause of jaundice in pregnant women.

Purpose:

  • To review the impact of pregnancy on liver physiology.
  • To discuss common and acquired liver diseases during gestation.
  • To highlight specific viral hepatitis concerns in pregnancy.

Summary:

  • Pregnancy-related liver conditions and acquired viral hepatitis are significant concerns.
  • Hepatitis E and Herpes Simplex Virus can present aggressively in pregnancy.
  • Hepatitis C does not adversely affect pregnancy outcomes but poses a transmission risk.

Impact:

  • Informs healthcare providers about managing liver diseases in pregnant patients.
  • Emphasizes the importance of monitoring and preventing viral hepatitis transmission.
  • Contributes to improved maternal and neonatal health outcomes by addressing liver health during pregnancy.