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Updated: Jul 10, 2026
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Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents
Published on: October 26, 2016
Development of endovascular stent-grafts
R J Hinchliffe1, B R Hopkinson
1Department of Vascular and Endovascular Surgery, University Hospital, Nottingham, UK. robhinchliffe@hotmail.com
Summary
Endovascular stent-grafts have evolved significantly, overcoming early complications to offer durable aortic aneurysm repair. Medical engineering advancements have expanded treatment options for previously untreatable conditions.
Area of Science:
- Medical Engineering
- Vascular Surgery
- Interventional Cardiology
Background:
- Early endovascular aortic stent-graft procedures in the 1990s faced significant complications like deployment failure, need for open surgery, and aneurysm rupture.
- Improvements in stent-graft design and technology by the mid-1990s led to successful aortic aneurysm exclusion with reduced morbidity and mortality.
Purpose of the Study:
- To review the key developments in endovascular aortic stent-grafting.
- To highlight the role of medical engineering and technology in advancing these treatments.
Main Methods:
- Review of historical data and clinical outcomes of endovascular aortic stent-grafting.
- Analysis of technological advancements and their impact on procedural success and long-term durability.
- Examination of recent multi-centre randomized controlled trials comparing endovascular and open repair.
Main Results:
- Initial challenges with stent-graft deployment and durability have been largely overcome.
- Recent trials show reduced aneurysm-related mortality with endovascular repair compared to open surgery.
- Current indications are expanding, enabling treatment of complex aortic aneurysms and maintenance of aortic side branch perfusion.
Conclusions:
- Endovascular aortic stent-grafting has matured into a safe and effective treatment for aortic aneurysms.
- Ongoing innovation in medical engineering continues to expand the applicability and improve the outcomes of these minimally invasive procedures.
