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Tourette syndrome and obsessive-compulsive disorder
Paul J Lombroso1, Lawrence Scahill
1Child Study Center, Yale University School of Medicine, New Haven, CT 06520, United States. paul.lombroso@yale.edu
Brain & Development
|October 17, 2007
Summary
Tourette syndrome and obsessive-compulsive disorder are complex neuropsychiatric disorders. Current research combines neurobiology, behavioral interventions, and advanced models to understand their causes and improve treatments.
Area of Science:
- Neuroscience
- Psychiatry
- Genetics
Background:
- Tourette syndrome (TS) and obsessive-compulsive disorder (OCD) are prevalent neuropsychiatric conditions.
- These disorders attract multidisciplinary research, including neuroimaging, epidemiology, and neuroimmunology.
Purpose of the Study:
- To review current understanding of Tourette syndrome and obsessive-compulsive disorder.
- To discuss clinical features, available treatments, and emerging research directions.
Main Methods:
- Review of clinical phenomenology and treatment options.
- Discussion of new psychopharmacological agents and behavioral interventions.
- Analysis of longitudinal studies and research models for etiological insights.
Main Results:
- Current treatments integrate pharmacotherapy with behavioral interventions, informed by neurobiology.
- Longitudinal studies offer insights into pathophysiology and natural disease course.
- Advances in research models aim to elucidate molecular etiologies.
Conclusions:
- Understanding the neurobiology of TS and OCD is crucial for developing effective treatments.
- Multidisciplinary approaches and ongoing research are essential for clarifying the complex etiologies of these disorders.
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