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Updated: Jul 10, 2026

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Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine
Published on: June 24, 2019
Epitheliotropic lymphoma in a squirrel (Sciurus sp.).
Shelley P Honnold1, Iyampillai Arun, Greg Saturday
1Department of Veterinary Pathology, Armed Forces Institute of Pathology, Building 54, Room G117, Washington, DC 20306, USA. honnolds@afip.osd.mil
Summary
This study reports the first known case of epitheliotropic lymphoma in a squirrel. Surgical removal was successful, with no recurrence observed 10 months post-operation.
Area of Science:
- Veterinary oncology
- Wildlife pathology
Background:
- Epitheliotropic lymphoma is a rare skin cancer affecting various species.
- Alopecia and dermal thickening are common presenting signs.
Observation:
- A 12-year-old male squirrel presented with a thoracic skin lesion.
- Initial diagnostics ruled out common causes of alopecia like fungal or mite infections.
Findings:
- Histopathology and immunohistochemistry confirmed epitheliotropic lymphoma of T-cell origin.
- Surgical excision was performed with complete removal of the tumor.
Implications:
- This case expands the known host range for epitheliotropic lymphoma.
- Highlights the importance of considering rare neoplastic conditions in wildlife, even with non-specific signs.

