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Published on: November 6, 2019
Peritonsillar infiltration with tramadol improves pediatric tonsillectomy pain
1Department of Otorhinolaryngology, Faculty of Medicine, Cairo University, Cairo, Egypt. amratef@dr.com
Insights
Submucosal infiltration of tramadol effectively reduced postoperative pain in children after tonsillectomy. This method provided superior pain control compared to placebo, reducing the need for additional analgesics.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Otolaryngology
Background:
- Post-tonsillectomy pain management in children is challenging.
- Tramadol is a known effective analgesic.
- Evaluating novel drug delivery methods for pediatric pain is crucial.
Purpose of the Study:
- To assess the efficacy and safety of submucosal tramadol infiltration for pain control in pediatric tonsillectomy patients.
- To compare tramadol submucosal infiltration with placebo for postoperative analgesia.
- To evaluate the impact on analgesic requirements and sedation.
Main Methods:
- Prospective, double-blinded, placebo-controlled study.
- 40 pediatric patients undergoing bipolar diathermy tonsillectomy.
- Randomized to receive submucosal infiltration of tramadol (2 mg/kg) or normal saline.
Main Results:
- Tramadol submucosal infiltration provided superior postoperative analgesia for 4 hours.
- Patients receiving tramadol required significantly fewer paracetamol doses in the first 12 hours.
- No significant differences in sedation scores were noted between groups.
Conclusions:
- Submucosal infiltration of tramadol is an effective strategy for superior postoperative pain management in children after tonsillectomy.
- This method offers a promising alternative for enhancing analgesia and reducing rescue medication needs.
- Tramadol submucosal infiltration demonstrates a favorable safety profile in this pediatric population.
Abstract:
Pain control in pediatric patients undergoing tonsillectomy remains a dilemma. Tramadol is reported to be an effective analgesic. This prospective, double-blinded, placebo-controlled study was performed to evaluate the analgesic efficacy and safety of submucosal infiltration of tramadol on postoperative pain in children after standard bipolar diathermy tonsillectomy. Following standard bipolar diathermy tonsillectomy was performed, 40 patients were randomized to receive submucoasl infiltration with 2 mg kg(-1) tramadol in 3 ml of normal saline (1.5 ml per tonsil) or normal saline only. The patients in each group were compared postoperatively with regard to the quality of pain control using the objective pain scale (OPS), sedation score and their analgesic requirements. Peritonsillar infiltration of tramadol (group 2) provided superior postoperative analgesia to placebo (group 1) for 4 h after surgery. In addition, group 1 received significantly more doses of paracetamol than group 2 in order to maintain analgesia in the first 12 h after recovery from anesthesia. Peritonsillar infiltration of tramadol appears to be an effective method of providing superior analgesia in the postoperative period when compared to placebo.
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