Related Experiment Video
Updated: Jul 10, 2026

08:52
Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Update on adolescent immunization: pertussis, meningococcus, HPV, and the future
Sylvia H Yeh1, Jay M Lieberman
1University of California, Los Angeles, USA. syeh@labiomed.org
Cleveland Clinic Journal of Medicine
|October 19, 2007
Summary
New vaccines for pertussis, meningococcal disease, and human papillomavirus (HPV) are available for adolescents. Routine check-ups for 11- to 12-year-olds offer a key opportunity for these crucial immunizations and health guidance.
Area of Science:
- Public Health
- Immunology
- Adolescent Medicine
Background:
- New vaccines for pertussis, meningococcal disease, and human papillomavirus (HPV) infection have been licensed since January 2005.
- Adolescents and preadolescents are identified as the primary target recipients due to their elevated risk for these specific infections.
Purpose of the Study:
- To highlight the importance of newly licensed vaccines for adolescent populations.
- To emphasize the role of routine health visits in adolescent immunization and risk-behavior counseling.
Main Methods:
- Review of vaccine licensing and target populations.
- Analysis of the utility of routine health visits for immunization and guidance.
Main Results:
- Availability of new vaccines against pertussis, meningococcal disease, and HPV.
- Identification of 11- to 12-year-old visits as optimal for immunization and anticipatory guidance.
Conclusions:
- Routine health visits for 11- to 12-year-olds are critical opportunities for administering new vaccines.
- Immunization and anticipatory guidance during these visits can mitigate risks associated with pertussis, meningococcal disease, and HPV infection in adolescents.
Related Concept Videos
Vaccinations
Overview
Cancer Vaccines
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Vaccines
Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Smallpox
Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
Infectious Diseases and Their Occurrence
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Poliomyelitis
Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
